The first issue (July 1968) featured a painted, color cover with a 52-page black-and-white Spider-Man story, "Lo, This Monster!", by writer Stan Lee, with art by penciler John Romita, Sr. and inker Jim Mooney. A 10-page origin story, "In The Beginning!", was by Lee, penciler Larry Lieber, and inker Bill Everett.
The feature story was reprinted in color, with some small alterations and bridging material by Gerry Conway, in The Amazing Spider-Man #116-118 (Jan.-March 1973) as "Suddenly...the Smasher!", "The Deadly Designs of the Disruptor!", and "Countdown to Chaos!" (with additional inking by Tony Mortellaro on the latter two). These versions were themselves reprinted in Marvel Tales #95-97 (Sept.-Oct. 1978).
The second and final issue (Nov. 1968) also sported a painted cover, and now the interior was in color as well. Lee, Romita and Mooney again collaborated on its single story, "The Goblin Lives!", featuring the Green Goblin. A next-issue box at the end promoted the planned contents of the unrealized issue #3, "The Mystery of the TV Terror". A version of the Goblin story, trimmed by 18 pages, was reprinted in The Amazing Spider-Man Annual #9 (1973), and portions of the TV Terror costume were reused for the costume of the Prowler.